2-[4-(N-叔丁氧羰基)哌嗪-1-基]嘧啶-5-硼酸频哪醇酯合成路线 (共 3 条)
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 3,4,7,8-tetra-methyl-1,10-phenanthroline in tetrahydrofuran T=20°C; 30 h; Inert atmosphereGlovebox;
参考文献
Larsen, Matthew A.; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 11 p. 4287 - 4299
反应条件
potassium acetate; palladium diacetate in N,N-dimethyl-formamide T=85°C; 16 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 11 p. 5361 - 5379
反应条件
1: potassium carbonate / acetonitrile / 23 h / 120 °C / |Inert atmosphere 2: bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 3,4,7,8-tetra-methyl-1,10-phenanthroline / tetrahydrofuran / 30 h / 20 °C / |Inert atmosphere; |Glovebox View Scheme
参考文献
Journal of the American Chemical Society, , vol. 136, # 11 p. 4287 - 4299