(R)-(+)-2-(4-羟基苯氧基)丙酸合成路线 （共 15 条）
反应条件
1: 2,6-dichloro-benzooxazole; (R)-(+)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide in N,N-dimethyl-formamide T=50 - 60°C; 2 h; 2: With 2,4,6-trichloro-1,3,5-triazine in N,N-dimethyl-formamide T=5 - 25°C; 1.16667 h; 3: ethanol in N,N-dimethyl-formamide
参考文献
Kalhor, Mehdi; Dadras, Akbar; Mobinikhaledi, Akbar; Tajik, Hassan
Journal of the Chilean Chemical Society, 2011 , vol. 56, # 4 p. 833 - 836
反应条件
1: 2,6-dichloro-benzooxazole; (R)-(+)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide in N,N-dimethyl-formamide T=50 - 60°C; 2 h; 2: With 2,4,6-trichloro-1,3,5-triazine in N,N-dimethyl-formamide T=5 - 25°C; 1.16667 h; 3: ethanol in N,N-dimethyl-formamide
参考文献
Kalhor, Mehdi; Dadras, Akbar; Mobinikhaledi, Akbar; Tajik, Hassan
Journal of the Chilean Chemical Society, 2011 , vol. 56, # 4 p. 833 - 836
反应条件
1: 3-chloro-2-fluoro-5-(trifluoro-methyl)pyridine; (R)-(+)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide in N,N-dimethyl-formamide T=50 - 60°C; 2 h; 2: With 2,4,6-trichloro-1,3,5-triazine in N,N-dimethyl-formamide T=5 - 25°C; 1.16667 h; 3: methanol in N,N-dimethyl-formamide
参考文献
Kalhor, Mehdi; Dadras, Akbar; Mobinikhaledi, Akbar; Tajik, Hassan
Journal of the Chilean Chemical Society, 2011 , vol. 56, # 4 p. 833 - 836
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide 2: With hydrogenchloride in water; N,N-dimethyl-formamide
参考文献
Chinese Chemical Letters, , vol. 22, # 5 p. 535 - 538
反应条件
1: (R)-(+)-2-(4-hydroxyphenoxy)propionic acid With potassium carbonate in water; acetonitrile T=50 - 75°C; 3 h; 2: 3,4-difluorobenzylnitrile in water; acetonitrile T=135°C; P=3501.01 Torr; 7 h; 3: 1-bromo-butane in water; acetonitrile T=100°C; P=1742.66 Torr; 6 h; Product distribution / selectivity;
参考文献
Dow AgroSciences LLC
Patent: US2009/112015 A1, 2009 ;
Location in patent: Page/Page column 2 ;
