L-八氢吲哚-2-羧酸苄酯对甲苯磺酸盐合成路线 （共 4 条）
反应条件
in toluene 4 h; Heating;
参考文献
Pascard; Guilhem; Vincent; Remond; Portevin; Laubie
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 663 - 669
反应条件
1: 66 percent / H2 / 10percent Pd/C / acetic acid / 18 h / 50 °C / 36775.4 Torr 2: 93 percent / toluene / 4 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 2 p. 663 - 669
反应条件
benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide in dichloromethane T=20 - 25°C;
参考文献
EP1679072 A1, ;
Page/Page column 7 ;
反应条件
1: (2S,3aS,7aS)-2-lt;(benzyloxy)carbonylgt;perhydroindole tosylate; triethylamine in ethyl acetate T=25°C; 2: (S)-N-[(S)-1-(ethoxycarbonyl)butyl]alanine With benzotriazol-1-ol; dicyclohexyl-carbodiimide in ethyl acetate T=15 - 25°C; 3 h; Product distribution / selectivity;
参考文献
WO2005/37788 A1, ;
Page/Page column 42-43 ;
