acetyl chloride; sodium iodide in acetonitrile T=20°C; 3 h; Inert atmosphere;

1: 5-Bromo-2-iodo-4-methyl-pyridine With iso-propylmagnesium bromide in tetrahydrofuran T=-15 - -10°C; 1 h; 2: N,N-dimethyl-formamide in tetrahydrofuran T=-15 - 0°C; 1 h;