thionyl chloride

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342940', constants.ctx, '0')">sodium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />&nbsp;Yield given;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1.) n-BuLi / 1.) THF, hexane, -60 deg C, 10 min, 2.) -65 deg C, 30 min<br />2: propionic acid / 145 - 180 &deg;C<br />3: 10percent aq. NaOH / 6 h / Heating<br /> <br /> &nbsp;