2-甲氨基-3-硝基-6-甲氧基吡啶合成路线 （共 4 条）
反应条件
hydrogen; 10percent Pd/C in 1,4-dioxane T=80°C; Catalytic hydrogenation; 5 h;
参考文献
Oguchi; Wada; Honma; Tanaka; Kaneko; Sakakibara; Ohsumi; Serizawa; Fujiwara; Horikoshi; Fujita
Journal of Medicinal Chemistry, 2000 , vol. 43, # 16 p. 3052 - 3066
反应条件
sodium chloride; sodium methylate in methanol
参考文献
Sankyo Company, Limited
Patent: US5624935 A1, 1997 ;
反应条件
in methanol
T=20°C; Methoxylation; 3 h;
参考文献
Oguchi; Wada; Honma; Tanaka; Kaneko; Sakakibara; Ohsumi; Serizawa; Fujiwara; Horikoshi; Fujita
Journal of Medicinal Chemistry, 2000 , vol. 43, # 16 p. 3052 - 3066
反应条件
1: 86 percent / Na2CO3 / ethanol / 8 h / 20 °C
2: 91 percent / methanol / 3 h / 20 °C
View Scheme
参考文献
Oguchi; Wada; Honma; Tanaka; Kaneko; Sakakibara; Ohsumi; Serizawa; Fujiwara; Horikoshi; Fujita
Journal of Medicinal Chemistry, 2000 , vol. 43, # 16 p. 3052 - 3066
