3,5-二异丙氧基苯甲酸甲酯合成路线 （共 5 条）
反应条件
caesium carbonate in acetonitrile T=85°C; 12 h; Heating / reflux;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2008/154563 A1, 2008 ;
Location in patent: Page/Page column 72-73 ;
WO 2008/154563 A1
反应条件
sodium hydride in DMF (N,N-dimethyl-formamide)
参考文献
WO2003/106405 A1, ;
Page 194-196 ;
WO 03/106405 A1
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 16 h;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 2 p. 183 - 186
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Smidrkal, Jan; Harmatha, Juraj; BudiSinsky, Milo; Vokae, Karel; ZIDEKc, Zdenik; Kmoniekova, Eva; Merkl, Roman; Filip, Vladimir
Collection of Czechoslovak Chemical Communications, 2010 , vol. 75, # 2 p. 175 - 186
反应条件
1: 7.34 g / lithium aluminium hydride / diethyl ether / 0.25 h / Heating
2: 13.6 g / manganese dioxide / benzene / 5 h / Heating
View Scheme
参考文献
Sargent, Melvyn V.; Stanojevic, Edi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1919 - 1921
