1,1'-(2-羟基-4,6-二甲氧基-1,3-亚苯基)二-1-丙酮合成路线 （共 3 条）
反应条件
Multi-step reaction with 6 steps 1: 87 percent / TFA; MCPBA / CH2Cl2 / 16 h / 0 - 5 °C2: 99 percent / aq. HCl / methanol / 2 h / Heating3: 98 percent / DIPEA / CH2Cl2 / 20 °C4: 240 mg / DMAP / CH2Cl2 / 3 h / 20 °C5: 75 percent / NaOMe / methanol / 2 h / Heating6: 74 percent / H2 / 10 percent Pd/C / methanol / 0.07 h
参考文献
Enders, Dieter; Geibel, Gunter; Osborne, Simon Chemistry - A European Journal, 2000 , vol. 6, # 8 p. 1302 - 1309
反应条件
Multi-step reaction with 2 steps 1: 87 percent / TFA; MCPBA / CH2Cl2 / 16 h / 0 - 5 °C2: 99 percent / aq. HCl / methanol / 2 h / Heating
参考文献
Enders, Dieter; Geibel, Gunter; Osborne, Simon Chemistry - A European Journal, 2000 , vol. 6, # 8 p. 1302 - 1309
反应条件
Multi-step reaction with 3 steps 1: 87 percent / TFA; MCPBA / CH2Cl2 / 16 h / 0 - 5 °C2: 99 percent / aq. HCl / methanol / 2 h / Heating3: 98 percent / DIPEA / CH2Cl2 / 20 °C
参考文献
Enders, Dieter; Geibel, Gunter; Osborne, Simon Chemistry - A European Journal, 2000 , vol. 6, # 8 p. 1302 - 1309
