1-溴-2-(苯氧基甲基)苯合成路线 （共 20 条）
参考文献
Huston et al.
Journal of the American Chemical Society, 1933 , vol. 55, p. 2146,2148
参考文献
Huston et al.
Journal of the American Chemical Society, 1933 , vol. 55, p. 2146,2148
反应条件
1: 94 percent / NBS; BPO / CCl4 / 5 h / Heating
2: K2CO3 / butan-2-one
View Scheme
参考文献
Yoshimi, Yasuharu; Maeda, Hajime; Hatanaka, Minoru; Mizuno, Kazuhiko
Tetrahedron, 2004 , vol. 60, # 42 p. 9425 - 9431
反应条件
1.1: N-chloro-succinimide; dimethylsulfide / dichloromethane
2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C / Inert atmosphere
2.2: 3.17 h
View Scheme
参考文献
Majmudar, Jaimeen D.; Hodges-Loaiza, Heather B.; Hahne, Kalub; Donelson, James L.; Song, Jiao; Shrestha, Liza; Harrison, Marietta L.; Hrycyna, Christine A.; Gibbs, Richard A.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 283 - 295
参考文献
Huston et al.
Journal of the American Chemical Society, 1933 , vol. 55, p. 2146,2148
反应条件
1: 2,9-dimethyl-1,10-phenanthroline; potassium tert-butylate / benzene / 24 h / 100 °C / Inert atmosphere
2: pyridinium chlorochromate / dichloromethane / 20 °C
View Scheme
参考文献
Sun, Chang-Liang; Gu, Yi-Fan; Huang, Wei-Ping; Shi, Zhang-Jie
Chemical Communications, 2011 , vol. 47, # 35 p. 9813 - 9815
反应条件
palladium diacetate; potassium carbonate; 2-Ph2P-2'-(Me2N)biphenyl in N,N-dimethyl acetamide
T=125°C; 2 h;
参考文献
Campeau, Louis-Charles; Parisien, Mathieu; Leblanc, Melissa; Fagnou, Keith
Journal of the American Chemical Society, 2004 , vol. 126, # 30 p. 9186 - 9187
反应条件
bis-triphenylphosphine-palladium(II) chloride; sodium acetate in N,N-dimethyl acetamide
T=160°C; 2 h;
参考文献
Ames, D.E.; Opalko, A.
Tetrahedron, 1984 , vol. 40, # 10 p. 1919 - 1926
反应条件
tetrabutylammomium bromide; potassium acetate; palladium diacetate in N,N-dimethyl acetamide; water
T=90°C; 6 h; SonicationInert atmosphere;
参考文献
Zhang, Lei; Geng, Mei; Teng, Peng; Zhao, Dan; Lu, Xi; Li, Jian-Xin
Ultrasonics Sonochemistry, 2012 , vol. 19, # 2 p. 250 - 256
反应条件
1: 99 percent Chromat. / Pd(OAc)2; PCy3*HBF4; K2CO3 / N,N-dimethyl-acetamide / 130 °C
2: BBr3 / CH2Cl2; heptane / 4 h / 20 °C
View Scheme
参考文献
Campeau, Louis-Charles; Parisien, Mathieu; Jean, Annie; Fagnou, Keith
Journal of the American Chemical Society, 2006 , vol. 128, # 2 p. 581 - 590
