2: triethylamine / CH2Cl2 / Ambient temperature 3: 0.8 g / HCl / ethanol / 48 h / Ambient temperature View Scheme

1: aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 2: NaBH3CN / ethanol / 3 h 3: H2 / 10percent Pd/C / ethanol / 4 h 4: 2.) conc. NH4OH / 1.) EtOH, RT, 16 h, 2.) EtOH, RT, 30 min View Scheme

1: 95 percent / K2CO3 / dimethylformamide / 1 h / 100 °C 2: 96 percent / aq. KOH / ethanol 3: oxalyl chloride / benzene; dimethylformamide / 1 h / Ambient temperature 4: aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 5: NaBH3CN / ethanol / 3 h 6: H2 / 10percent Pd/C / ethanol / 4 h 7: 2.) conc. NH4OH / 1.) EtOH, RT, 16 h, 2.) EtOH, RT, 30 min View Scheme

1: 96 percent / aq. KOH / ethanol 2: oxalyl chloride / benzene; dimethylformamide / 1 h / Ambient temperature 3: aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 4: NaBH3CN / ethanol / 3 h 5: H2 / 10percent Pd/C / ethanol / 4 h 6: 2.) conc. NH4OH / 1.) EtOH, RT, 16 h, 2.) EtOH, RT, 30 min View Scheme

1: H2 / 10percent Pd/C / ethanol / 4 h 2: 2.) conc. NH4OH / 1.) EtOH, RT, 16 h, 2.) EtOH, RT, 30 min View Scheme

1: oxalyl chloride / benzene; dimethylformamide / 1 h / Ambient temperature 2: aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 3: NaBH3CN / ethanol / 3 h 4: H2 / 10percent Pd/C / ethanol / 4 h 5: 2.) conc. NH4OH / 1.) EtOH, RT, 16 h, 2.) EtOH, RT, 30 min View Scheme

1: aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 2: NaBH3CN / ethanol / 3 h 3: H2 / 10percent Pd/C / ethanol / 4 h 4: 2.) conc. NH4OH / 1.) EtOH, RT, 16 h, 2.) EtOH, RT, 30 min View Scheme

hydrogenchloride in ethanol 48 h; Ambient temperature;

1: triethylamine / CH2Cl2 / Ambient temperature 2: 0.8 g / HCl / ethanol / 48 h / Ambient temperature View Scheme

ammonium hydroxide 1.) EtOH, RT, 16 h, 2.) EtOH, RT, 30 min; Yield given. Multistep reaction;