1,2,3,4-四氢咔唑合成路线 （共 202 条）
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in tetrahydrofuran; water T=0°C;
参考文献
Sissouma, Drissa; Collet, Sylvain C.; Guingant, Andre Y.
Synlett, 2004 , # 14 p. 2612 - 2614
反应条件
1: 5percent Pd/C / various solvent(s) / 7 h / Heating 2: NaOH / acetone; H2O / 2 h / Heating View Scheme
参考文献
Humne, Vivek; Dangat, Yuvraj; Vanka, Kumar; Lokhande, Pradeep
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 27 p. 4832 - 4836
反应条件
potassium hydroxide beim Schmelzen;
参考文献
Zanetti
Chemische Berichte, 1893 , vol. 26, p. 2006
Gazzetta Chimica Italiana, 1893 , vol. 23 II, p. 296
反应条件
1: 1,2,3,4,10,11-hexahydrocarbazole With potassium hydroxide in dimethyl sulfoxide T=25°C; 1 h; Inert atmosphere; 2: 2-bromo-1-ethanol in dimethyl sulfoxide T=0 - 25°C; Inert atmosphere;
参考文献
Kimura, Tsutomu; Hosokawa-Muto, Junji; Asami, Kenji; Murai, Toshiaki; Kuwata, Kazuo
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 11 p. 5675 - 5679
反应条件
tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide in dichloromethane 2 h;
参考文献
Benkovics, Tamas; Guzei, Ilia A.; Yoon, Tehshik P.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 48 p. 9153 - 9157
参考文献
Das; Jamal; Choudhury
Journal of the Indian Chemical Society, 1990 , vol. 67, # 1 p. 72 - 73
反应条件
potassium; toluene anschl. mit Acetylchlorid;
参考文献
Witkop
Journal of the American Chemical Society, 1950 , vol. 72, p. 614,619
反应条件
1: 16.7 percent / aluminium chloride / 1,2-dichloro-ethane / cooling, 1 h, then rt, 24 h 2: 46.3 percent / 10 percent Pd/C / xylene / 2.5 h / 140 °C View Scheme
参考文献
Patel, B. P. J.
Journal of the Indian Chemical Society, 1985 , vol. 62, # 7 p. 534 - 536
反应条件
n-butyllithium; potassium tert-butylate
1.) Et2O, -78 deg C -> room temperature, 2.) -78 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Naruse, Yuji; Ito, Yoshitaka; Inagaki, Satoshi
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2256 - 2258
反应条件
potassium hydroxide in dimethyl sulfoxide
2.5 h; Ambient temperature;
参考文献
Yokoyama, Yuusaku; Okuyama, Naomi; Iwadate, Shinji; Momoi, Tokuko; Murakami, Yasuoki
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 5 p. 1319 - 1329
