1,2,3,4-四氢咔唑合成路线 （共 202 条）
反应条件
potassium hydroxide; acetone
参考文献
Eisch, John J.; Dua, Suresh K.; Kovacs, Csaba A.
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4437 - 4444
反应条件
ammonia; sodium; iron nitrate (III)
anschl. mit Benzylchlorid;
参考文献
Nakazaki; Isoe
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1159,1167
Chem.Abstr., 1957 , p. 17877
反应条件
1: 1,2,3,4,10,11-hexahydrocarbazole With (η3-allyl)2Pd(cod)BF4; bis[2-(diphenylphosphino)phenyl] ether in toluene
T=20°C; 0.0833333 h; Inert atmosphere;
2: PhCH2OCO2Me With N,O-bis-(trimethylsilyl)-acetamide; triethyl borane in hexane; toluene
T=50°C; 18 h; Inert atmosphere;
参考文献
Zhu, Ye; Rawal, Viresh H.
Journal of the American Chemical Society, 2012 , vol. 134, # 1 p. 111 - 114
反应条件
1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 0 °C / |Inert atmosphere
1.2: 20 °C / |Inert atmosphere
2.1: (η3-allyl)2Pd(cod)BF4; potassium phenolate; triethyl borane; bis[2-(diphenylphosphino)phenyl] ether / toluene / 16 h / 75 °C / |Inert atmosphere
View Scheme
参考文献
Chen, Jun; Cook, Matthew J.
Organic Letters, 2013 , vol. 15, # 5 p. 1088 - 1091
反应条件
ammonia; sodium; iron nitrate (III)
anschl. mit Benzylchlorid;
参考文献
Nakazaki; Isoe
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1159,1167
Chem.Abstr., 1957 , p. 17877
参考文献
Nakazaki; Isoe
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1159,1167
Chem.Abstr., 1957 , p. 17877
反应条件
methyl-magnesium iodide
1) Et2O 2) 24 h, r.t.; Yield given. Multistep reaction;
参考文献
Rodriguez, Jose-Gonzalo; Andres, Angel San
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1293 - 1299
反应条件
hydrogen fluoride; dihydrogen peroxide; SbF5
T=-20°C; 0.05 h;
参考文献
Berrier, Christian; Jacquesy, Jean-Claude; Jouannetaud, Marie-Paule; Renoux, Alain
Tetrahedron Letters, 1986 , vol. 27, # 38 p. 4565 - 4568
反应条件
1: 1,2,3,4,10,11-hexahydrocarbazole With sodium hydride in tetrahydrofuran; mineral oil
T=0°C; 1 h;
2: benzoyl chloride in tetrahydrofuran; mineral oil
T=20°C;
参考文献
Nakano, Yuji; Lupton, David W.
Chemical Communications, 2014 , vol. 50, # 14 p. 1757 - 1760
反应条件
diethyl ether
Behandlung des Reaktionsprodukts mit Benzoylchlorid;
参考文献
Perkin; Plant
Journal of the Chemical Society, 1923 , vol. 123, p. 680,688
