甲基-4-羟基-2-甲基-d3-2H-1,2-苯并噻嗪-3-羧酸酯1,1-二氧化物合成路线 (共 3 条)
反应条件
sodium hydroxide in ethanol 24 h;
参考文献
Balssa, Frederic; Bonnaire, Yves
Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 3 p. 207 - 210
反应条件
1: 64.2 percent / MeONa / dimethylsulfoxide / 0.07 h / 30 °C 2: 52.6 percent / aq. NaOH / ethanol / 24 h View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 50, # 3 p. 207 - 210
反应条件
1.1: NaH / dimethylformamide / 0.17 h / 0 °C 1.2: 65 percent / 3.5 h / 20 - 80 °C 2.1: 64.2 percent / MeONa / dimethylsulfoxide / 0.07 h / 30 °C 3.1: 52.6 percent / aq. NaOH / ethanol / 24 h View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 50, # 3 p. 207 - 210