1: methanephosphonic acid dimethyl ester With potassium hexamethylsilazane in tetrahydrofuran; toluene T=-78 - -20°C; 2: (2R,3S,E)-((1R,2S)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl) 3-hydroxy-5-iodo-2,4-dimethylpent-4-enoate With isopropylmagnesium chloride in tetrahydrofuran; diethyl ether; toluene T=-78 - 20°C; 3: With ammonium chloride in tetrahydrofuran; diethyl ether; water; toluene