1,4-二氢-6-甲氧基-4-氧代-3-喹啉羧酸甲酯合成路线 （共 7 条）
反应条件
sodium hydroxide in water T=80°C; Hydrolysis; 0.5 h;
参考文献
Mohri, Kunihiko; Kanie, Akihiko; Horiguchi, Yoshie; Isobe, Kimiaki
Heterocycles, 1999 , vol. 51, # 10 p. 2377 - 2384
反应条件
1: toluene / 6 h / Heating
2: 90 percent / Eaton's reagent / 90 °C
View Scheme
参考文献
Zewge, Daniel; Chen, Cheng-Yi; Deer, Curtis; Dormer, Peter G.; Hughes, Dave L.
Journal of Organic Chemistry, 2007 , vol. 72, # 11 p. 4276 - 4279
反应条件
1: toluene / 6 h / Heating
2: 90 percent / Eaton's reagent / 90 °C
View Scheme
参考文献
Zewge, Daniel; Chen, Cheng-Yi; Deer, Curtis; Dormer, Peter G.; Hughes, Dave L.
Journal of Organic Chemistry, 2007 , vol. 72, # 11 p. 4276 - 4279
反应条件
1: 58 percent / tetrahydrofuran; diethyl ether / 20 °C
2: 64 percent / diphenyl ether / 0.5 h / 230 °C
3: 79 percent / NaOH / H2O / 1 h / 60 °C
4: 0.33 h / 180 °C / heating with powdered glass
View Scheme
参考文献
Mohri, Kunihiko; Kanie, Akihiko; Horiguchi, Yoshie; Isobe, Kimiaki
Heterocycles, 1999 , vol. 51, # 10 p. 2377 - 2384
反应条件
1: 79 percent / NaOH / H2O / 1 h / 60 °C
2: 0.33 h / 180 °C / heating with powdered glass
View Scheme
参考文献
Mohri, Kunihiko; Kanie, Akihiko; Horiguchi, Yoshie; Isobe, Kimiaki
Heterocycles, 1999 , vol. 51, # 10 p. 2377 - 2384
反应条件
1: 64 percent / diphenyl ether / 0.5 h / 230 °C
2: 79 percent / NaOH / H2O / 1 h / 60 °C
3: 0.33 h / 180 °C / heating with powdered glass
View Scheme
参考文献
Mohri, Kunihiko; Kanie, Akihiko; Horiguchi, Yoshie; Isobe, Kimiaki
Heterocycles, 1999 , vol. 51, # 10 p. 2377 - 2384
反应条件
T=180°C; Decarboxylation; 0.333333 h; heating with powdered glass;
参考文献
Mohri, Kunihiko; Kanie, Akihiko; Horiguchi, Yoshie; Isobe, Kimiaki
Heterocycles, 1999 , vol. 51, # 10 p. 2377 - 2384
