1: 1-bromo-3-butynol With Gly-Ni-(S)-2-[N-(N-benzylpropyl)amino]benzophenone; sodium hydroxide in N,N-dimethyl-formamide T=20°C; 0.1 h; Inert atmosphere; 2: With hydrogenchloride in methanol T=60°C; 0.5 h; 3: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in 1,4-dioxane T=0 - 20°C;