4,4'-[1,6-己烷二基二(氧基)]二苯甲腈合成路线 (共 5 条)
反应条件
nitric acid; trifluoroacetic acid in acetic anhydride T=45°C; 24 h;
参考文献
Tidwell; Jones; Geratz; Ohemeng; Cory; Hall
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1252 - 1257
反应条件
sodium ethanolate
48 h; Heating;
参考文献
Tidwell; Jones; Geratz; Ohemeng; Cory; Hall
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1252 - 1257
参考文献
Ashley et al.
Journal of the Chemical Society, 1942 , p. 103,107
反应条件
hydrogenchloride; ethanol
Behandeln des Reaktionsprodukts mit aethanol. Ammoniak;
参考文献
Ashley et al.
Journal of the Chemical Society, 1942 , p. 103,107
反应条件
1: HCl (gas) / benzene / 72 h / Ambient temperature
2: ethanol. NH3 / 6 h / 50 °C
View Scheme
参考文献
Tidwell; Jones; Geratz; Ohemeng; Cory; Hall
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1252 - 1257