1.1: 82 percent / DMAP; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride / CH2Cl2 / 15 h / 20 °C 2.1: 42 percent / K2CO3 / pyridine / 1 h / Heating 3.1: 92 percent / K2CO3 / acetonitrile / 3 h / 60 °C 4.1: AlBr3 / acetonitrile / 1 h / 0 °C 4.2: 97 percent / aq. HCl / methanol; acetonitrile / 1 h / Heating 5.1: Ag2O; 4 Angstroem molecular sieves / CH2Cl2 / 36 h / 40 °C 6.1: hydrogen / Pd/C / ethyl acetate / 14 h / 20 °C 6.2: 18 mg / K2CO3 / methanol / 1.5 h / 70 °C View Scheme