1: 60 percent / Na(Hg) / methanol; H2O / 0.75 h 2: 75 percent / Et3N / CH2Cl2 / 0.17 h / -78 °C 3: 100 percent / H2; Et3N / Pd/C / ethyl acetate / 3 h / 760.05 Torr 4: Bu4NF / tetrahydrofuran / 12 h View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587189', constants.ctx, '0')">hydrogen</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '19211235', constants.ctx, '0')">rhodium on alumina</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />P=760.051&nbsp;Torr;&nbsp;12&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: Et₃N / CH₂Cl₂ / 1 h / 0 &deg;C<br />2: 279.8 mg / NaI / 1,2-dimethoxy-ethane / 12 h / Heating<br />3: 100 percent / sym-collidine / CH₂Cl₂ / 0.25 h / -78 &deg;C<br />4: 99 percent / H₂ / Rh-Al₂O₃ / tetrahydrofuran / 12 h / 760.05 Torr<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 97 percent / K₂CO₃ / tetrahydrofuran; H₂O; methanol / 2.5 h<br />2: Et₃N / CH₂Cl₂ / 1 h / 0 &deg;C<br />3: 279.8 mg / NaI / 1,2-dimethoxy-ethane / 12 h / Heating<br />4: 100 percent / sym-collidine / CH₂Cl₂ / 0.25 h / -78 &deg;C<br />5: 99 percent / H₂ / Rh-Al₂O₃ / tetrahydrofuran / 12 h / 760.05 Torr<br /> <br /> &nbsp;