2-(4-甲氧基-3-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)苯基)乙酸甲酯合成路线 （共 3 条）
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in dimethyl sulfoxide
T=40 - 80°C; 14 h;
参考文献
MERCK and CO., INC.
Patent: WO2007/81569 A2, 2007 ;
Location in patent: Page/Page column 93 ;
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in ethylene glycol dimethyl ether
T=110°C; 18 h; Heating;
参考文献
Ghosh, Samir; Kumar, A. Sanjeev; Mehta; Soundararajan
Synthesis, 2009 , # 19 p. 3322 - 3326
反应条件
1: iodine; silver sulphate / methanol / 1 h / 20 °C
2: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / dimethyl sulfoxide / 14 h / 40 - 80 °C / Inert atmosphere
View Scheme
参考文献
MERCK SHARP and DOHME CORP.; LU, Zhijian; CHEN, Yi-Heng; SMITH, Cameron; LI, Hong; THOMPSON, Christopher, F.; SWEIS, Ramzi; SINCLAIR, Peter; KALLASHI, Florida; HUNT, Julianne; ADAMSON, Samantha, E.; DONG, Guizhen; ONDEYKA, Debra, L.; QIAN, Xiaoxia; SUN, Wanying; VACHAL, Petr; ZHAO, Kake
Patent: WO2012/58187 A1, 2012 ;
WO 2012/058187 A1
