2-氨基-4-三氟嘧啶-5-硼酸频哪醇酯合成路线 （共 3 条）
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane T=115°C; 6 h;
参考文献
WO2008/98058 A1, ;
Page/Page column 63-64 ;
WO 2008/098058 A1
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate in 1,4-dioxane T=115°C; 4 h; Inert atmosphere;
参考文献
NOVARTIS AG; Fairhurst, Robin Alec; Furet, Pascal; Kalthoff, Frank Stephan; Lerchner, Andreas; Rueeger, Heinrich
Patent: US2014/135330 A1, 2014 ;
Location in patent: Paragraph 0218 ;
反应条件
1: N-bromosuccinmide / acetonitrile / 4.5 h / 20 °C / |Darkness 2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate / 1,4-dioxane / 4 h / 115 °C / |Inert atmosphere View Scheme
