1-(6-三氟甲基-吡啶-2-基)乙酮合成路线 （共 2 条）
反应条件
1: 2-bromo-6-(trifluoromethyl)pyridine With n-butyllithium in diethyl ether
T=-78°C; 0.416667 h; Inert atmosphere;
2: N,N-dimethyl acetamide in diethyl ether
T=-78 - 23°C; Inert atmosphere;
参考文献
So, Sonia S.; Auvil, Tyler J.; Garza, Victoria J.; Mattson, Anita E.
Organic Letters, 2012 , vol. 14, # 2 p. 444 - 447
反应条件
in N,N-dimethyl-formamide
T=100°C; 8 h; Sealed tubeInert atmosphere;
参考文献
Mormino, Michael G.; Fier, Patrick S.; Hartwig, John F.
Organic Letters, 2014 , vol. 16, # 6 p. 1744 - 1747
