3-(4,4,5,5-四甲基-1,3,2-二氧硼烷-2-基)-1H-吡咯并[2,3-B]吡啶合成路线 （共 4 条）
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 3,4,7,8-tetra-methyl-1,10-phenanthroline in tetrahydrofuran
T=80°C; 4 h; Inert atmosphereGlovebox; regioselective reaction;
参考文献
Preshlock, Sean M.; Plattner, Donald L.; Maligres, Peter E.; Krska, Shane W.; Maleczka Jr., Robert E.; Smith III, Milton R.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 49 p. 12915 - 12919
Angew. Chem., 2013 , vol. 125, # 49 p. 13153 - 13157,5
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 3,4,7,8-tetra-methyl-1,10-phenanthroline in tetrahydrofuran
T=80°C; 4 h; Inert atmosphereGlovebox;
参考文献
Larsen, Matthew A.; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 11 p. 4287 - 4299
反应条件
1: With trifluoroacetic acid in dichloromethane; water
2 h; Inert atmosphere;
2: With sodium carbonate in dichloromethane
Inert atmosphere;
参考文献
Larsen, Matthew A.; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 11 p. 4287 - 4299
反应条件
1.1: bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 3,4,7,8-tetra-methyl-1,10-phenanthroline / tetrahydrofuran / 19 h / 80 °C / |Inert atmosphere; |Glovebox
2.1: trifluoroacetic acid / dichloromethane; water / 2 h / |Inert atmosphere
2.2: |Inert atmosphere
View Scheme
参考文献
Larsen, Matthew A.; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 11 p. 4287 - 4299
