(+-)-6-氨基-alpha-羟基-9H-嘌呤-9-丙酸合成路线 （共 6 条）
反应条件
1: conc. HCl / H2O / 4 h / Heating
2: acetic acid / 1) 0 deg C, 5 h, 2) r.t., overnight
3: conc. HCl / 6 h / Heating
View Scheme
参考文献
Holy, Antonin
Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 9 p. 2148 - 2166
反应条件
potassium phosphate; sodium salt of phosphorous acid in water
T=37°C; var. pH; Rate constant;
参考文献
De Clercq; Holy
Journal of Medicinal Chemistry, 1985 , vol. 28, # 3 p. 282 - 287
反应条件
potassium phosphate; sodium salt of phosphorous acid in water
T=37°C; var. pH; Rate constant;
参考文献
De Clercq; Holy
Journal of Medicinal Chemistry, 1985 , vol. 28, # 3 p. 282 - 287
反应条件
potassium phosphate; sodium salt of phosphorous acid in water
T=37°C; var. pH; Rate constant;
参考文献
De Clercq; Holy
Journal of Medicinal Chemistry, 1985 , vol. 28, # 3 p. 282 - 287
反应条件
1: acetic acid / 1) 0 deg C, 5 h, 2) r.t., overnight
2: conc. HCl / 6 h / Heating
View Scheme
参考文献
Holy, Antonin
Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 9 p. 2148 - 2166
反应条件
1: 80 percent / conc. H2SO4 / 4 h / Heating
2: 88.9 percent / NaBH4 / ethanol / 1) 0 deg C, 2 h, 2) r.t., overnight
View Scheme
参考文献
Holy, Antonin
Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 9 p. 2148 - 2166
