2-硼-5-甲基硫代-1H-吲哚-1-羧酸-1-(1,1-二甲基乙基)酯合成路线 （共 3 条）
反应条件
1: With tri-isopropoxy-borane; lithium diisopropyl amide in tetrahydrofuran
T=0 - 5°C;
2: With phosphate buffer in tetrahydrofuran
pH=6.0; Further stages.;
参考文献
Mizuta, Masahiro; Seio, Kohji; Miyata, Kenichi; Sekine, Mitsuo
Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5046 - 5055
反应条件
1.1: 99 percent / 4-(N,N-dimethylamino)pyridine / CH2Cl2 / 1 h / 20 °C
2.1: triisopropyl borate; LDA / tetrahydrofuran / 0 - 5 °C
2.2: 97 percent / aq. phosphate buffer / tetrahydrofuran / pH 6.0
View Scheme
参考文献
Mizuta, Masahiro; Seio, Kohji; Miyata, Kenichi; Sekine, Mitsuo
Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5046 - 5055
反应条件
1.1: 99 percent / 4-(N,N-dimethylamino)pyridine / CH2Cl2 / 1 h / 20 °C
2.1: triisopropyl borate; LDA / tetrahydrofuran / 0 - 5 °C
2.2: 97 percent / aq. phosphate buffer / tetrahydrofuran / pH 6.0
View Scheme
参考文献
Mizuta, Masahiro; Seio, Kohji; Miyata, Kenichi; Sekine, Mitsuo
Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5046 - 5055
