5-(氨基甲基)-2-氯苯胺合成路线 （共 2 条）
反应条件
sodium tetrahydroborate; CoCl2.6H2O in methanol
T=0 - 20°C;
参考文献
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; HENDRICKSON, Thomas, Francis; HO, Koc-Kan; SAUNDERS, Michael, David; STEVENS, Brian, John; SWIERCZEK, Krzysztof; WRIGHT, Kevin, Bret
Patent: WO2013/62945 A1, 2013 ;
Location in patent: Page/Page column 104 ;
WO 2013/062945 A1
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Zhao, Guohua; Bolton, Scott A.; Kwon, Chet; Hartl, Karen S.; Seiler, Steven M.; Slusarchyk, William A.; Sutton, James C.; Bisacchi, Gregory S.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 309 - 312
