6-氯-3-碘-2-(三氟甲基)吡啶合成路线 (共 2 条)
反应条件
n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-75 - -72°C; 1.83333 h;
参考文献
US2007/185058 A1, ;
Page/Page column 17 ;
反应条件
1: With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-76 - -73°C; 1.5 h;
2: With iodine in tetrahydrofuran; hexane
T=-75°C; 1.16667 h;
参考文献
Conte, Aurelia; Kuehne, Holger; Luebbers, Thomas; Mattei, Patrizio; Maugeais, Cyrille; Mueller, Werner; Pflieger, Philippe
Patent: US2007/185058 A1, 2007 ;
Location in patent: Page/Page column 16-17 ;