1: 50 percent / toluene / 72 h / Heating 2: 70 percent / LiAlH4 / diethyl ether / 0.25 h / 0 °C View Scheme

1: styrene; Oppolzer’s sultam acrylamide With copper(l) chloride; Grubbs-Hoveyda ruthenium catalyst in ethyl acetate Heating; 2: With sodium periodate; cerium(III) chloride; tetrabutylammonium (meta)periodate in various solvents T=0°C; 3: methanol With methylmagnesium bromide in tetrahydrofuran; dichloromethane T=0°C; Further stages. Title compound not separated from byproducts.;

sodium tetrahydroborate in dichloromethane; water T=0°C; 1 h; competition reaction: competition rate constant; Rate constant;