6-氯-1-苯基-1-己酮合成路线 （共 12 条）
反应条件
1: 1-bromo-5-chloro-pentane With ethylene dibromide; lithium chloride; zinc; chloro-trimethyl-silane; iodine in tetrahydrofuran T=50°C; 12 h; 2: benzoyl chloride With dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran T=25°C; 0.5 h;
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 36 p. 6040 - 6044
反应条件
zinc dibromide in tetrahydrofuran T=25°C; 6 h;
参考文献
Zheng, Bin; Srebnik, Morris
Journal of Organic Chemistry, 1995 , vol. 60, # 11 p. 3278 - 3279
反应条件
aluminium trichloride in tetrachloromethane; benzene
参考文献
US4372953 A1, ;
US 4372953 A
反应条件
(i) aq. NaOCl, AcOH, (ii) (heating); Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 26, p. 3523 - 3525
反应条件
palladous nitrate in 1,4-dioxane T=120°C; 5 h;
参考文献
Journal of the American Chemical Society, , vol. 124, # 43 p. 12670 - 12671
反应条件
aluminium trichloride
参考文献
Journal of the American Chemical Society, , vol. 109, # 10 p. 3057 - 3062
反应条件
1: BuLi / tetrahydrofuran 2: 80 percent / Et2O-BF3 / acetone; H2O View Scheme
参考文献
Bulletin de la Societe Chimique de France, , # 1 p. 83 - 92
反应条件
in diethyl ether T=-40 - 20°C; Inert atmosphere;
参考文献
Pablo, Oscar; Guijarro, David; Yus, Miguel
Journal of Organic Chemistry, 2013 , vol. 78, # 18 p. 9181 - 9189
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; acetonitrile 16 h;
参考文献
Fleming, Fraser F.; Funk, Lee A.; Altundas, Ramazan; Sharief, Vaqar
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9414 - 9416
反应条件
sodium hydroxide in 1,4-dioxane; water
参考文献
Bird, Roger; Griffiths, Gwerydd; Griffiths, Gwynfor F.; Stirling, Charles J. M.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 579 - 584
