3-(三氟甲基硫代)苯甲酸合成路线 （共 14 条）
反应条件
hydrogenchloride in acetic acid T=110°C; 6 h;
参考文献
Kondratenko, N. V.; Kolomeitsev, A. A.; Popov, V. I.; Il'chenko, A. Ya.; Korzhenevskaya, N. G.; et al.
J. Gen. Chem. USSR (Engl. Transl.), 1983 , vol. 53, # 11 p. 2500 - 2505,2254 - 2258
反应条件
in N,N-dimethyl-formamide T=115 - 120°C; 4 h;
参考文献
Munavalli, S.; Hassner, A.; Rossman, D. I.; Singh, S.; Rohrbaugh, D. K.; Ferguson, C. P.
Journal of Fluorine Chemistry, 1995 , vol. 73, # 1 p. 7 - 12
反应条件
1: m-carboxybenzenediazonium tetrafluoroborate With copper(I) isothiocyanate; sodium isothiocyanate; caesium carbonate in acetonitrile T=20°C; 0.166667 h; Inert atmosphere; 2: (trifluoromethyl)-trimethylsilane in acetonitrile T=20°C; 16 h;
参考文献
Danoun, Gregory; Bayarmagnai, Bilguun; Gruenberg, Matthias F.; Goossen, Lukas J.
Chemical Science, 2014 , vol. 5, # 4 p. 1312 - 1316
反应条件
1: 79 percent / liquid ammonia / 0.5 h / Irradiation; PRK-4 mercury lamp 2: 90 percent / HCl / acetic acid / 6 h / 110 °C View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 53, # 11 p. 2500 - 2505,2254 - 2258
反应条件
1: tetrahydrofuran 2: (i) Br2, (irradiation), CCl4, (ii) aq. HNO3 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 29, p. 895 - 898
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 31, p. 1315 - 1320,1219 - 1223
反应条件
1: (i) aq. HCl, NaNO2, (ii) /BRN= 3587243/, aq. CuCl 2: aq. NaOH View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 31, p. 1315 - 1320,1219 - 1223
反应条件
(i) Br2, (irradiation), CCl4, (ii) aq. HNO3; Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 29, p. 895 - 898
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether 6 h; Heating;
参考文献
El-Fehail Ali; Dandridge; Gleason; et al.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 947 - 952
反应条件
1: 55 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 6 h / Heating 2: SOCl2 / 18 h / 25 °C 3: NaI / ethanol; H2O / 1.5 h / Heating View Scheme
参考文献
El-Fehail Ali; Dandridge; Gleason; et al.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 947 - 952
