3-(三氟甲基硫代)苯甲酸合成路线 （共 14 条）
反应条件
in diethyl ether T=-78 - 20°C;
参考文献
Wang, Aihua; Prouty, Catherine P.; Pelton, Patricia D.; Yong, Maria; Demarest, Keith T.; Murray, William V.; Kuo, Gee-Hong
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 4 p. 1432 - 1435
反应条件
1: 55 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 6 h / Heating 2: SOCl2 / 18 h / 25 °C View Scheme
参考文献
El-Fehail Ali; Dandridge; Gleason; et al.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 947 - 952
反应条件
dihydrogen peroxide; acetic acid
参考文献
ABBOTT LABORATORIES
Patent: WO2009/148452 A1, 2009 ;
Location in patent: Page/Page column 47 ;
反应条件
N,N-dimethyl-formamide
T=0 - 20°C; 4 h;
参考文献
VICURON PHARMACEUTICALS, INC.
Patent: WO2004/7444 A2, 2004 ;
Location in patent: Page 132 ;
