2-[(4-氯苯基)异二氮烯]丙二腈合成路线 （共 5 条）
反应条件
1: 4-chloro-aniline With hydrogenchloride in water
2: With sodium nitrite in water
Cooling;
3: malononitrile With sodium acetate in ethanol; water
T=20°C; Cooling;
参考文献
Al-Matar, Hamad Mohamed; Khalil, Khaled Dessouky; Al-Dorri, Doa'A Mohamed; Elnagdi, Mohamed Helmy
Molecules, 2010 , vol. 15, # 5 p. 3302 - 3310
反应条件
1: 65 percent / aq. HCl; NaOCOCH3 / ethanol / 2 h / 20 °C
2: 60 percent / AcOH; AcONa; NH2OSO3H / 4 h / Heating
View Scheme
参考文献
Al-Saleh, Balkis; El-Apasery, Morsy A.; Elnagdi, Mohamed Hilmy
Journal of Chemical Research, 2004 , # 8 p. 578 - 580
反应条件
ethanol; sodium acetate
参考文献
Lythgoe; Todd; Topham
Journal of the Chemical Society, 1944 , p. 315
反应条件
(i) aq. NaNO2, HCl, (ii) /BRN= 1742274/, aq. NaOH, MeOH, (iii) aq. HCl; Multistep reaction;
参考文献
Coenen,M.
Justus Liebigs Annalen der Chemie, 1961 , vol. 640, p. 85 - 98
反应条件
(i) NaNO2, (ii) /BRN= 773697/, aq. NaOAc; Multistep reaction;
参考文献
Barber,H.J. et al.
Journal of the Chemical Society, 1961 , p. 2828 - 2843
