hydrogenchloride; aluminium trichloride in water

hydrogenchloride; aluminium trichloride 1.) dichloroethane, reflux, 1.5 h, 2.) reflux, 4 h; Yield given. Multistep reaction;

1: 93 percent / dimethylformamide / 18 h / Ambient temperature 2: 1.) hydrogen, 2.) HCl / 1.) 20percent Pd/C / 1.) glacial AcOH, 50 psi, 18 h, 2.) EtOH, 2-propanol 3: 1.) BBr3, 2.) HCl / 1.) 1,2-dichloroethane, reflux, 1.5 h, 2.) 2-propanol, 25 deg C, 2 h 4: 2.) aq. NH4OH / 1.) EtOH, reflux, 7 d 5: methylhydrazine / methanol / 25 °C View Scheme

1: 93 percent / dimethylformamide / 18 h / Ambient temperature 2: 1.) hydrogen, 2.) HCl / 1.) 20percent Pd/C / 1.) glacial AcOH, 50 psi, 18 h, 2.) EtOH, 2-propanol 3: BBr3 / 1,2-dichloro-ethane / 1.5 h / Heating View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 68 percent / NaH / tetrahydrofuran / 1.) 0 deg C, 30 min, 2.) 25 deg C, 12 h<br />2: 95 percent / trifluoroacetic anhydride, trifluoroacetic acid / 18 h / Ambient temperature<br /> <br /> &nbsp;