benzoic acid; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene T=110°C; 24 h; Title compound not separated from byproducts.;

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '635722', constants.ctx, '0')">(RS)-3-hydroxybut-1-yne</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=-78&deg;C;&nbsp;2&nbsp;h;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1071910', constants.ctx, '0')">3-phenyl-propionaldehyde</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=-78 - 20&deg;C;&nbsp;&nbsp;Further stages.;&nbsp;<br /> &nbsp;