1: [(6-trifluoromethylpyridin-3-yl)methyl](methyl)oxido- λ4- sulfanylidenecyanamide With N,N,N',N',N'',N''-hexamethylphosphoric triamide; potassium hexamethylsilazane in tetrahydrofuran T=-78°C; 0.333333 h; 2: methyl iodide in tetrahydrofuran 1 h;

sodium disulfite; NaMnO4 in dichloromethane; water T=3 - 30°C; 3.55 - 6.5 h; Cooling with ice; Product distribution / selectivity;

NaMnO4; acetic acid in water; acetonitrile T=15 - 20°C; 1.58333 - 1.75 h; Product distribution / selectivity;

1: [bis(acetoxy)iodo]benzene / dichloromethane / 0 - 20 °C 2: 3-chloro-benzenecarboperoxoic acid; potassium carbonate / ethanol; water / 1.5 h / 0 - 20 °C 3: N,N,N',N',N'',N''-hexamethylphosphoric triamide; potassium hexamethylsilazane / tetrahydrofuran; toluene / -78 - 20 °C View Scheme

1: 3-chloro-benzenecarboperoxoic acid; potassium carbonate / ethanol; water / 1.5 h / 0 - 20 °C 2: N,N,N',N',N'',N''-hexamethylphosphoric triamide; potassium hexamethylsilazane / tetrahydrofuran; toluene / -78 - 20 °C View Scheme

1: dimethyl sulfoxide 2: [bis(acetoxy)iodo]benzene / dichloromethane / 0 - 20 °C 3: 3-chloro-benzenecarboperoxoic acid; potassium carbonate / ethanol; water / 1.5 h / 0 - 20 °C 4: N,N,N',N',N'',N''-hexamethylphosphoric triamide; potassium hexamethylsilazane / tetrahydrofuran; toluene / -78 - 20 °C View Scheme