2-溴-3-二氟甲氧基吡啶合成路线 （共 3 条）
反应条件
1: copper(I) oxide; ammonium hydroxide / water; 2-methoxy-ethanol / 23 h / 100 °C 2: N-bromosuccinmide / acetonitrile / 0.17 h / 0 °C View Scheme
参考文献
Huang, Zilin; Jin, Jeff; Machajewski, Timothy; Antonios-McCrea, William R.; McKenna, Maureen; Poon, Daniel; Renhowe, Paul A.; Sendzik, Martin; Shafer, Cynthia; Smith, Aaron; Xu, Yongjin; Zhang, Qiong; Chen, Zheng
Patent: US2013/210818 A1, 2013 ;
反应条件
sodium hydroxide in N,N-dimethyl-formamide
T=55°C; 111 h;
参考文献
Huang, Zilin; Jin, Jeff; Machajewski, Timothy; Antonios-McCrea, William R.; McKenna, Maureen; Poon, Daniel; Renhowe, Paul A.; Sendzik, Martin; Shafer, Cynthia; Smith, Aaron; Xu, Yongjin; Zhang, Qiong; Chen, Zheng
Patent: US2013/210818 A1, 2013 ;
Location in patent: Paragraph 0414 ;
反应条件
ammonium hydroxide; 2-methoxy-ethanol; copper(I) oxide in water
T=100°C; 23 h;
参考文献
Huang, Zilin; Jin, Jeff; Machajewski, Timothy; Antonios-McCrea, William R.; McKenna, Maureen; Poon, Daniel; Renhowe, Paul A.; Sendzik, Martin; Shafer, Cynthia; Smith, Aaron; Xu, Yongjin; Zhang, Qiong; Chen, Zheng
Patent: US2013/210818 A1, 2013 ;
Location in patent: Paragraph 0415 ;
