1-(4-甲氧苯甲酰基)哌嗪合成路线 (共 6 条)
反应条件
1: 4-methoxy-benzoic acid With N-bromosuccinmide; triphenylphosphine in dichloromethane T=0 - 5°C; 0.25 h; 2: piperazine With pyridine in dichloromethane T=20°C; 0.583333 h;
参考文献
Synthetic Communications, , vol. 34, # 16 p. 2917 - 2924
反应条件
acetic acid in tetrahydrofuran T=20°C; Acylation; 1 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 6 p. 808 - 816
反应条件
1: SOCl2 / Heating 2: AcOH / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 6 p. 808 - 816
反应条件
hydrogenchloride in dimethyl sulfoxide; acetonitrile T=25°C; Substitution; Kinetics;
参考文献
Journal of Organic Chemistry, , vol. 65, # 18 p. 5659 - 5663
反应条件
water in dimethyl sulfoxide T=25°C; aminolysis; Kinetics;
参考文献
Canadian Journal of Chemistry, , vol. 77, # 5-6 p. 659 - 666
反应条件
in water; dimethyl sulfoxide T=25°C; Kinetics; Time;
参考文献
Bulletin of the Korean Chemical Society, , vol. 32, # 4 p. 1153 - 1157