反应条件
1: 4-bromo-2-pyridinecarboxylic acid With 1,1'-carbonyldiimidazole in N,N-dimethyl-formamide
0.25 h;
2: morpholine in N,N-dimethyl-formamide
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; COOK, Brian Nicholas; KUZMICH, Daniel
Patent: WO2011/56440 A1, 2011 ;
Location in patent: Page/Page column 58-59 ;
WO 2011/056440 A1
