2-(5-溴-3-甲氧基吡啶-2-基)乙腈合成路线 （共 3 条）
反应条件
lithium hexamethyldisilazane in tetrahydrofuran
T=20°C;
参考文献
Ple, Patrick A.; Jung, Frederic; Ashton, Sue; Hennequin, Laurent; Laine, Romuald; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Pasquet, Georges; Taylor, Sian
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3050 - 3055
反应条件
chloro-trimethyl-silane
T=50°C; 20 h;
参考文献
Morgentin, Remy; Jung, Frederic; Lamorlette, Maryannick; Maudet, Mickael; Menard, Morgan; Ple, Patrick; Pasquet, Georges; Renaud, Fabrice
Tetrahedron, 2009 , vol. 65, # 4 p. 757 - 764
反应条件
1: chloro-trimethyl-silane / 4 h / 65 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 6 h / 85 °C
3: dihydrogen peroxide / dichloromethane / 1.5 h / 20 °C
View Scheme
参考文献
Ple, Patrick A.; Jung, Frederic; Ashton, Sue; Hennequin, Laurent; Laine, Romuald; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Pasquet, Georges; Taylor, Sian
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3050 - 3055
