4-(4-溴-1H-吲唑-1-基)-6,7-二甲氧基噌啉合成路线 （共 1 条）
反应条件
1: 4-bromo-1H-indazole With n-butyllithium in isobutyramide
T=-30°C; 0.5 h;
2: 4-bromo-6,7-dimethoxycinnoline With triethylamine; tris-(dibenzylideneacetone)dipalladium(0) in isobutyramide
T=-30 - 85°C; 12.0833 h;
3: With methanol in dichloromethane
参考文献
AMGEN INC.; MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2007/98214 A1, 2007 ;
Location in patent: Page/Page column 57; 69 ;
