1-苯基哌嗪-2-酮盐酸盐合成路线 （共 3 条）
反应条件
hydrogenchloride; tributylphosphine; 1,1'-azodicarbonyl-dipiperidine in ethyl acetate
T=0 - 5°C;
参考文献
Weissman, Steven A.; Lewis, Stephanie; Askin, David; Volante; Reider, Paul J.
Tetrahedron Letters, 1998 , vol. 39, # 41 p. 7459 - 7462
反应条件
1: 60 °C
2: 83 percent Spectr. / 1.) tributylphosphine, 1,1'-(azocarbonyl)dipiperidine; 2.) ethanolic HCl / ethyl acetate / 0 - 5 °C
View Scheme
参考文献
Weissman, Steven A.; Lewis, Stephanie; Askin, David; Volante; Reider, Paul J.
Tetrahedron Letters, 1998 , vol. 39, # 41 p. 7459 - 7462
反应条件
1: isopropyl acetate, aq. potassium bicarbonate / 5 °C
2: 60 °C
3: 83 percent Spectr. / 1.) tributylphosphine, 1,1'-(azocarbonyl)dipiperidine; 2.) ethanolic HCl / ethyl acetate / 0 - 5 °C
View Scheme
参考文献
Weissman, Steven A.; Lewis, Stephanie; Askin, David; Volante; Reider, Paul J.
Tetrahedron Letters, 1998 , vol. 39, # 41 p. 7459 - 7462
