1: acetonitrile; H2O / 0.17 h 2: 86 percent / ZrCl4 / nitromethane / 0.03 h / Heating View Scheme

potassium tert-butylate; O-(2,4,6-trimethylbenzenesulfonyl)hydroxylamine in N,N-dimethyl-formamide T=0°C; 0.5 h;

aminomethylated polystyrene resin from Novabiochem in methanol; chloroform T=20°C; 24 h;

1: 86.6 percent / t-BuOK / dimethylformamide / 1.) r.t., 30 min, 2.) 80 deg C, 1.5 h 2: 91 percent / 70percent aq. HClO4 / dioxane / 1 h / Ambient temperature View Scheme