2,3-O-异亚丙基-L-古洛糖酸内酯合成路线 （共 3 条）
反应条件
1: 71 percent / imidazole / dimethylformamide / 2 h / -40 °C 2: pyridine; CH2Cl2 / 1 h / -30 °C 3: NaN3 / dimethylformamide / 3 h View Scheme
参考文献
Fleet, George W. J.; Ramsden, Nigel G.; Witty, David R.
Tetrahedron Letters, 1988 , vol. 29, # 23 p. 2871 - 2874
反应条件
1.1: (n-Bu)2SnO; MS 4A / benzene / Heating 1.2: 97 percent / iPr2NEt / dimethylformamide / 3 h / 20 °C 2.1: pyridine / CH2Cl2 / 2 h / -40 °C 3.1: NaN3 / dimethylformamide / 20 °C 4.1: 65 percent / H2 / Raney Ni / methanol / 4 h / 20 °C 5.1: 68 percent / 4M HCl / dioxane / 6 h / 20 °C View Scheme
参考文献
Fleet, George W. J.; Ramsden, Nigel G.; Witty, David R.
Tetrahedron, 1989 , vol. 45, # 1 p. 319 - 326
反应条件
sodium cyanoborohydride; periodic acid in tetrahydrofuran
参考文献
Bleriot, Yves; Gretzke, Dirk; Kruelle, Thomas M.; Butters, Terry D.; Dwek, Raymond A.; Nash, Robert J.; Asano, Naoki; Fleet, George W.J.
Carbohydrate Research, 2005 , vol. 340, # 18 p. 2713 - 2718
