2-(4-氨基-1H-吡唑-1-基)乙醇合成路线 (共 2 条)
反应条件
hydrogen; palladium 10 on activated carbon in ethanol
P=760.051 Torr; 0.5 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/99326 A1, 2007 ;
Location in patent: Page/Page column 113 ;
WO 2007/099326 A1
反应条件
1: With potassium carbonate in acetonitrile
T=60°C; 18 h;
2: With palladium on activated charcoal; hydrogen in methanol; acetonitrile
18 h;
参考文献
CELLZOME LIMITED; OXENFORD, Sally; HOBSON, Andrew; OLIVER, Kathryn; RAMSDEN, Nigel
Patent: WO2012/143320 A1, 2012 ;
Location in patent: Page/Page column 39 ;
WO 2012/143320 A1