Glen, Robert C.; Martin, Graeme R.; Hill, Alan P.; Hyde, Richard M.; Woollard, Patrick M.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3566 - 3580
hydrogenchloride; hydrogen; palladium on barium sulfate in water P=760 Torr; 4 h;
参考文献
Herbert, Richard B.; Knaggs, Andrew R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 1 p. 103 - 108
1: 99 percent / SOCl2 / Ambient temperature 2: 46 percent / sodium borohydride / ethanol; H2O / 2.5 h / Heating 3: 36 percent / aq. KOH / toluene / 1 h / 0 °C 4: 97 percent / H2, aq. 2 N HCl / 10percent Pd/C / ethanol; ethyl acetate 5: 1.) aq. HCl, NaNO2, 2.) SnCl2 / 1.) from -5 deg C to 0 deg C, 30 min, 2.) RT, 3 h 6: 0.21 g / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Glen, Robert C.; Martin, Graeme R.; Hill, Alan P.; Hyde, Richard M.; Woollard, Patrick M.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 18 p. 3566 - 3580