4-(3-(甲基氨基)-1-(噻吩-2-基)丙基)萘-1-醇合成路线 （共 4 条）
反应条件
ammonia in water
T=40°C; 1.5 h;
参考文献
EGIS GYOGYSZERGYAR NYRT
Patent: WO2007/105021 A2, 2007 ;
Location in patent: Page/Page column 31 ;
反应条件
hydrogenchloride in ethyl acetate
T=25°C; 0.75 h;
参考文献
Biswas, Sujoy; Karanjai, Keya
Patent: US2009/275760 A1, 2009 ;
Location in patent: Page/Page column 4 ;
反应条件
sodium hydroxide in toluene
参考文献
Ranbaxy Laboratories Limited
Patent: EP2107057 A1, 2009 ;
Location in patent: Page/Page column 5 ;
反应条件
1: With sodium hydroxide in water; toluene
T=25°C; pH=11 - 12; 0.166667 h;
2: With hydrogenchloride in water; ethyl acetate
T=5 - 20°C; 4.5 h;
参考文献
Ranbaxy Laboratories Limited
Patent: EP2107057 A1, 2009 ;
Location in patent: Page/Page column 4-5 ;
