反应条件
1: 2,4-dihydroxy-benzaldehyde With 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) in acetonitrile
T=22°C; 168 h; Inert atmosphereCooling;
2: diethyl malonate With morpholine; acetic acid in methanol
Inert atmosphereCoolingHeating;
参考文献
3M INNOVATIVE PROPERTIES COMPANY; ROSCOE, Stephen, B.; CHOU, Shih-Hung; MOELLER, Stephanie, J.; MILLER, Jesse, D.; HALVERSON, Kurt, J.; BJORK, Jason, W.
Patent: WO2012/134724 A1, 2012 ;
Location in patent: Page/Page column 36-38 ;