1: K2CO3 / dimethylformamide / 1.) 3 h, 2.) 60 - 65 deg C, 3 h, 3.) RT, overnight 2: 0.17 h / 245 - 250 °C 3: m-chloroperbenzoic acid / CH2Cl2 / 24 h / 10 - 20 °C 4: Kieselgel 60 / CH2Cl2 / 24 h / Ambient temperature View Scheme
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1: 2-chlorophenol With sodium hydride in mineral oil T=20°C; 0.5 h; Schlenk techniqueInert atmosphere; 2: 1,4-dibromo-butane in mineral oil 2 h; Schlenk techniqueInert atmosphere;
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Yi, Jun; Lu, Xi; Sun, Yan-Yan; Xiao, Bin; Liu, Lei
Angewandte Chemie - International Edition, 2013 , vol. 52, # 47 p. 12409 - 12413
Angew. Chem., 2013 , vol. 125, # 47 p. 12635 - 12639,5