反应条件
1: 70 percent
2: n-BuLi / 1.) THF, ether, -90 deg C, 0.5 h; 2.) -75 deg C
3: 79 percent / N(Et)3, 2,4-Dinitrobenzenesulfenyl chloride / CH2Cl2 / 0.75 h / Heating
4: m-Chloroperbenzoic acid (85percent) / CCl4 / 0.17 h / 20 - 30 °C
5: NBS, Dibenzoyl peroxide / CCl4 / 7 h / Heating
6: Benzyltriethylammonium chloride / acetonitrile / 22 h / 30 °C
7: 1.) t-BuOCl; 2.) DBU / 1.) CCl4, 4 h, reflux, irradiation; 2.) CH2Cl2, 30 deg C, 2 h
8: p-TsOH / CH2Cl2 / 0.5 h / 35 °C
View Scheme
参考文献
Reich, Ieva L.; Reich, Hans J.
Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3721 - 3727
