2-氨基-4-甲基苯酚合成路线 (共 127 条)
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=23°C; 5 h;
参考文献
VICURON PHARMACEUTICALS INC.
Patent: US2006/211603 A1, 2006 ;
Location in patent: Page/Page column 68 ;
反应条件
palladium 10 on activated carbon; hydrogen in ethanol P=1551.49 Torr; 4 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 5 p. 1679 - 1689
反应条件
molecular sieve; boron trifluoride diethyl etherate in dichloromethane Ambient temperature;
参考文献
Evans, Emily F.; Lewis, Norman J.; Kapfer, Isabelle; Macdonald, Gregor; Taylor, Richard J. K.
Synthetic Communications, 1997 , vol. 27, # 11 p. 1819 - 1825
反应条件
sodium hydroxide; sodium dithionite in water 0.00611111 h; microwave irradiation;
参考文献
Peng, Yanqing; Song, Gonghua; Ding, Fang
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 9 p. 2021 - 2023
反应条件
Thiourea sulfone; sodium hydroxide in water T=50°C; 1 h;
参考文献
Farkas, Renata; Toerincsi, Mercedesz; Kolonits, Pal; Fekete, Jenoe; Alonso, Oscar Jimenez; Novak, Lajos
Central European Journal of Chemistry, 2010 , vol. 8, # 2 p. 300 - 307
反应条件
Thiourea sulfone; sodium hydroxide in water T=50°C; 1 h;
参考文献
Farkas, Renata; Toerincsi, Mercedesz; Kolonits, Pal; Fekete, Jenoe; Alonso, Oscar Jimenez; Novak, Lajos
Central European Journal of Chemistry, 2010 , vol. 8, # 2 p. 300 - 307
反应条件
hydrogen; nickel in water; isopropyl alcohol T=59.85°C; Title compound not separated from byproducts;
参考文献
Russian Journal of Physical Chemistry A, , vol. 77, # 8 p. 1266 - 1269
反应条件
Saccharomyces cerevisiae in ethanol 8 h; phosphate buffer (pH 7.2); Yield given;
参考文献
Chemical Communications, , # 11 p. 1015 - 1016
反应条件
trifluoroacetic acid in dichloromethane T=-20°C; 6 h; ΔH(excit.), ΔG(excit.), ΔS(excit.); Thermodynamic dataRate constantKinetics;
参考文献
Journal of the American Chemical Society, , vol. 114, # 25 p. 9795 - 9806
反应条件
hydrogen; nickel in water; isopropyl alcohol T=1.85°C; P=760 Torr; Product distributionKinetics;
参考文献
Russian Journal of Physical Chemistry A, , vol. 78, # 6 p. 877 - 881